Dr Edgar Hartsuiker
Senior Lecturer in Biomedical Sciences (Cancer Biology)
Publications
2023
- Published
Alblihy , A., Ali , R., Algethami, M., Ritchie, A. A., Shoqafi, A., Alqahtani, S., Mesquita, K. A., Toss, M. S., Ordóñez-Morán , P., Jeyapalan, J. N., Dekker , L., Salerno, M., Hartsuiker, E., Grabowska , A. M., Rakha, E. A., Mongan, N. P. & Madhusudan, S., 30 Jun 2023, In: International journal of molecular sciences. 24, 13
Research output: Contribution to journal › Article › peer-review
2020
- Published
Blackburn, C., Tai, H., Salerno, M., Wang, X., Senan, C., Ratcliffe, I., Hartsuiker, E. & Wang, W., Feb 2020, In: Data in Brief. 28, 104861.
Research output: Contribution to journal › Article › peer-review - Published
Böckemeier, L., Kraehenbuehl, R., Keszthelyi, A., Gasasira, M. U., Vernon, E., Beardmore, R., Broberg Vågbø, C., Chaplin, D., Collins, S., Krokan, H. E., Lambert, S. A. E., Paisz, B. & Hartsuiker, E., 29 May 2020, In: Science Advances. 6, 22, 9 p., eaaz4126.
Research output: Contribution to journal › Article › peer-review
2019
- Published
Blackburn, C., Tai, H., Salerno, M., Wang, X., Hartsuiker, E. & Wang, W., Nov 2019, In: European Polymer Journal. 120, 109259.
Research output: Contribution to journal › Article › peer-review
2018
- Published
Roguev, A., Ryan, C. J., Xu, J., Colson, I., Hartsuiker, E. & Krogan, N., Feb 2018, In: Cold Spring Harbor Protocols. 2018, 2
Research output: Contribution to journal › Article › peer-review - Published
Colson, I. & Hartsuiker, E., Feb 2018, In: Cold Spring Harbor Protocols. 2018, 2
Research output: Contribution to journal › Article › peer-review - Published
Roguev, A., Ryan, C. J., Hartsuiker, E. & Krogan, N. J., Feb 2018, In: Cold Spring Harbor Protocols. 2018, 2, p. 75-81 7 p.
Research output: Contribution to journal › Article › peer-review
2017
- Published
Fleck, O., Fahnøe, U., Løvschal, K. V., Gasasira Uwamahoro, M.-F., Marinova, I. N., Kragelund, B. B., Carr, A. M., Hartsuiker, E., Holmberg, C. & Nielsen, O., 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.
Research output: Contribution to journal › Article › peer-review
2015
- Published
Zech, J., Godfrey, E. L., Masai, H., Hartsuiker, E. & Dalgaard, J. Z., 22 Jul 2015, In: PLoS ONE. 10, 7
Research output: Contribution to journal › Article › peer-review - Published
Zhou, Z., Humphryes, N., van Eijk, P., Waters, R., Yu, S. R., Kraehenbuehl, R., Hartsuiker, E. & Reed, S. H., 6 Jul 2015, In: Nucleic Acids Research. 43, 15, p. 7360-7370
Research output: Contribution to journal › Article › peer-review
2011
- Published
Hartsuiker, E. & Tsubouchi, H. (Editor), 28 Apr 2011, DNA recombination: Methods and Protocols. Springer Science and Business Media LLC, p. 65-77
Research output: Chapter in Book/Report/Conference proceeding › Chapter
2010
- Published
Nakamura, K., Kogame, T., Oshiumi, H., Shinohara, A., Sumitomo, Y., Agama, K., Pommier, Y., Tsutsui, K. M., Tsutsui, K., Hartsuiker, E., Ogi, T., Takeda, S. & Taniguchi, Y., 22 Jan 2010, In: PLOS Genetics. 6, 1
Research output: Contribution to journal › Article › peer-review - Published
Durand-Dubief, M., Persson, J., Norman, U., Hartsuiker, E. & Ekwall K., [. V., 7 Jul 2010, In: EMBO Journal. 29, 13, p. 2126 - 2134
Research output: Contribution to journal › Article › peer-review
2009
- Published
Lloyd, J., Chapman, J. R., Clapperton, J. A., Haire, L. F., Hartsuiker, E., Li, J., Carr, A. M., Jackson, S. P. & Smerdon, S. J., 2 Oct 2009, In: Cell. 139, 1, p. 100-111
Research output: Contribution to journal › Article › peer-review - Published
Hartsuiker, E., Mizuno, K., Molnar, M., Kohli, J., Ohta, K. & Carr, A. M., Apr 2009, In: Molecular and Cellular Biology. 29, 7, p. 1671-1681 11 p.
Research output: Contribution to journal › Article › peer-review - Published
Hartsuiker, E., Neale, M. J. & Carr, A. M., 16 Jan 2009, In: Molecular Cell. 33, 1, p. 117-123
Research output: Contribution to journal › Article › peer-review - Published
Deshpande, G. P., Hayles, J., Hoe, K. L., Kim, D. U., Park, H. O. & Hartsuiker, E., 1 May 2009, In: DNA Repair. 8, 5, p. 672-679
Research output: Contribution to journal › Article › peer-review
2007
- Published
El-Khamisy, S. F., Hartsuiker, E. & Caldecott, K. W., 1 Oct 2007, In: DNA Repair. 6, 10, p. 1485-95 11 p.
Research output: Contribution to journal › Article › peer-review
2006
- Published
Raji, H. & Hartsuiker, E., 15 Oct 2006, In: Yeast. 23, 13, p. 963-76 14 p.
Research output: Contribution to journal › Article › peer-review
2005
- Published
Baur, M., Hartsuiker, E., Lehmann, E., Ludin, K., Munz, P. & Kohli, J., Feb 2005, In: Genetics. 169, 2, p. 551-61 11 p.
Research output: Contribution to journal › Article › peer-review
2004
- Published
Yamada, T., Mizuno, K.-I., Hirota, K., Kon, N., Wahls, W. P., Hartsuiker, E., Murofushi, H., Shibata, T. & Ohta, K., 21 Apr 2004, In: EMBO Journal. 23, 8, p. 1792-803 12 p.
Research output: Contribution to journal › Article › peer-review
2003
- Published
Werler, P. J. H., Hartsuiker, E. & Carr, A. M., 30 Jan 2003, In: Gene. 304, p. 133-41 9 p.
Research output: Contribution to journal › Article › peer-review
2002
- Published
Farah, J. A., Hartsuiker, E., Mizuno, K.-I., Ohta, K. & Smith, G. R., May 2002, In: Genetics. 161, 1, p. 461-8 8 p.
Research output: Contribution to journal › Article › peer-review - Published
Marchetti, M. A., Kumar, S., Hartsuiker, E., Maftahi, M., Carr, A. M., Freyer, G. A., Burhans, W. C. & Huberman, J. A., 28 May 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 11, p. 7472-7 6 p.
Research output: Contribution to journal › Article › peer-review
2001
- Published
Hartsuiker, E., Vaessen, E., Carr, A. M. & Kohli, J., 3 Dec 2001, In: EMBO Journal. 20, 23, p. 6660-71 12 p.
Research output: Contribution to journal › Article › peer-review - Published
Manolis, K. G., Nimmo, E. R., Hartsuiker, E., Carr, A. M., Jeggo, P. A. & Allshire, R. C., 15 Jan 2001, In: EMBO Journal. 20, 1-2, p. 210-21 12 p.
Research output: Contribution to journal › Article › peer-review
1999
- Published
Rudolph, C., Kunz, C., Parisi, S., Lehmann, E., Hartsuiker, E., Fartmann, B., Kramer, W., Kohli, J. & Fleck, O., Jan 1999, In: Molecular and Cellular Biology. 19, 1, p. 241-50 10 p.
Research output: Contribution to journal › Article › peer-review
1998
- Published
Hartsuiker, E., Bähler, J. & Kohli, J., Oct 1998, In: Molecular Biology of the Cell. 9, 10, p. 2739-50 12 p.
Research output: Contribution to journal › Article › peer-review
1994
- Published
Heyting, C., Dietrich, A. J., de Jong, J. H. & Hartsuiker, E., 1994, Chromosome Analysis Protocols. Gosden, J. R. (ed.). Vol. 29. p. 287-302 (Methods in Molecular Biology).
Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Activities
2022
The overall aim of the proposed research is to optimise and apply the range of assays we have developed to assess the genotoxic impact of some key anti-cancer (Gemcitabine) and anti-viral (Remdesivir and Molnupiravir) nucleoside analogues and publish this analysis as proof of principle and advertise the knowledge and expertise we have developed here in Wales. The proposed research involves a new collaboration between Ïã¸ÛÁùºÏ²Ê¹ÒÅÆ×ÊÁÏ applicants and the recently established company Broken String Biosciences Ltd., which offers assays that are complementary to the assays we have been developing. In the long term, we believe there is significant potential for impact and commercial exploitation of our assays, e.g. by influencing requirements for genotoxic assessment of nucleoside analogue drugs and offering our expertise and novel assays as a commercial service for pharmaceutical companies to assess the on- and off-target effects of candidate nucleoside analogue drugs.
Funding awarded through the Ïã¸ÛÁùºÏ²Ê¹ÒÅÆ×ÊÁÏ Innovation and Impact Award (Research Wales Innovation Funding). Value = £45,942
1 Apr 2022 – 31 Mar 2023
Activity: Other (Contributor)
Projects
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01/05/2024 – 28/02/2025 (Active)
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01/10/2022 – 31/03/2024 (Finished)
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01/10/2022 – 31/03/2024 (Finished)
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01/01/2021 – 31/01/2022 (Finished)
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01/01/2021 – 31/03/2024 (Finished)
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01/03/2020 – 31/03/2024 (Finished)
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01/10/2019 – 31/03/2024 (Finished)
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01/10/2018 – 01/08/2022 (Finished)
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01/10/2018 – 31/03/2024 (Finished)
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01/10/2018 – 31/03/2024 (Finished)
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01/11/2017 – 31/03/2024 (Finished)
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01/01/2016 – 30/04/2016 (Finished)
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01/09/2015 – 01/08/2019 (Finished)
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01/04/2015 – 01/08/2019 (Finished)
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01/01/2015 – 30/09/2023 (Finished)
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01/11/2014 – 31/10/2015 (Finished)
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01/01/2014 – 30/06/2017 (Finished)
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23/09/2013 – 01/08/2019 (Finished)
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01/06/2013 – 10/11/2017 (Finished)
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01/12/2011 – 30/11/2013 (Finished)
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01/10/2011 – 31/12/2014 (Finished)
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01/03/2011 – 01/08/2022 (Finished)
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01/10/2010 – 30/09/2014 (Finished)
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01/09/2010 – 31/08/2016 (Finished)